Phenibut Withdrawal | What You MUST Know

Curious about Phenibut withdrawal symptoms? Then this article is for you.

Users of Phenibut have reported incredible effects: reduced anxiety, more sociability, better sleep, and being in a gret mood. It seems like a bit of a “wonder drug” when talking about social situations, like going to the bar.

P.S: Click here to order Phenibut from the top vendor online!

But there are also rumors of Phenibut dependence, where people become addicted to the great feelings and face withdrawal effects when they stop.

Is there any truth to those rumors?

We’ve gone deep into the research literature to find out more about Phenibut withdrawal. Let’s get to it.

P.S: It should come as no surprise that I’m not a doctor or a lawyer. This is not legal or medical advice. The information presented on this site is purely entertainment. Always consult a medical professional before consuming any nootropics. Full disclaimer.

What is Phenibut?

To understand about Phenibut withdrawal, you first need to understand what Pheibut is and how it works.

Phenibut dependence is real and if you understand how dependence happens in general, you’ll understand why a person can become dependent on Phenibut.

Phenibut is a chain of amino acids that forms a chemical that looks a lot like a chemical that we make naturally in our brain called gamma-aminobutyric acid (more commonly known as GABA) [1]. GABA is a neurotransmitter.

Understanding Neurotransmitters

First, a brief lesson about the nervous system.

The nervous system is like the control center of the body. It includes the brain and spinal cord as well as all the nerves that run throughout your body. It’s responsible for receiving information from your body, sending it back to your brain to process, and then sending out signals back to the body to coordinate a response.

How does it send those signals? Through nerve cells called neurons. Those neurons communicate with each other using neurotransmitters. One cell releases neurotransmitters that communicate with specific cells on the next cell. The neurotransmitters are essential for the successful communication between neuron cells.

What does GABA do?

GABA is a neurotransmitter that inhibits action [1]. That doesn’t sound that interesting, but it’s actually super important. Imagine your neurons are like the turn signal or indicator on your car. It’s important to turn the signal on when you’re turning, but it’s also important to turn it off when you’re done turning. GABA is what turns the cells off.

Imagine you’re walking home at night and something scares you. Your body gets you ready for a “fight or flight” response. Your adrenaline pumps, your nervous system is excited, everything is turned on. But then you get home safe. You don’t want your body to still be in that excitable mode. It needs to calm down.

GABA does that. It’s what we call a “depressant”, which means that it “depresses” or slows down your nervous system.

Phenibut mimics GABA

Since it looks chemically like GABA, Phenibut mimics GABA and is able to bind to some of the same neuron receptors [1]. That means that Phenibut has some of the same effects as GABA. For example, it helps relax you, makes you feel less stressed, and gets you ready for sleep [1].

At low levels, Phenibut also results in the release of dopamine, another neurotransmitter that is associated with the pleasure center of the brain. It’s dopamine that’s responsible for the “high” or euphoric feeling that many users report feeling from Phenibut.

Together, these effects make Phenibut a powerful anxiolytic (a medication for addressing anxiety), a mood booster, and a sleep aid. It’s also often used for vestibular disorders like tics and stuttering because part of the reason for these disorders can be that there’s not the right balance of neurotransmitters [1].

Phenibut has been used by doctors in Russia and other countries of the former USSR since the 1960s when it was discovered, and many of these countries still use it today [1]. It’s very effective.

Phenibut HCL

Phenibut Side Effects and Safety

Great, so you know what it is and how it works. But is it safe to use?

Yes. It’s generally considered a very safe and effective substance [1].

However, there are some side effects and safety issues that anyone considering using Phenibut should take in mind and that researchers should consider for their “test subjects” [2].

Side effects are quite rare, and often people don’t experience these. But they can happen. Potential side effects include [2]:

  • Irritability
  • Drowsiness
  • Sedation
  • Nausea
  • Headache
  • Loss of balance
  • Hangover-like symptoms
  • Motor incoordination

Also uncommonly, people may experience an allergic reaction. Allergic reactions can happen anytime you take anything, but it’s still important to note. Common allergic reactions to Phenibut include itching and rashes on the skin.

Avoid side effects by not using Phenibut if you have lots of allergies and by not taking too large of a dose. See the dosing guide for more information about Phenibut dosage.

Interaction Effects

Another set of effects aren’t side effects exactly, but it’s important to know when you’re taking Phenibut.

Since Phenibut is a “depressant” or something that slows down your nervous system, it’s important not to combine it with other medications or substances that are also depressants. The combination of two different depressants could have stronger, longer-lasting, and sometimes even dangerous effects.

It’s like how you would never take alcohol with sleeping pills; by themselves, both are fine, but together they can be dangerous.

Other common depressants include [3]:

  • Alcohol
  • Benzodiazepines
  • Anti-convulsant medications
  • Anti-psychotic medications
  • Opioids
  • Sedatives
  • Anti-anxiety medications

It’s easy to avoid interaction effects. Simply don’t take Phenibut with any of the above medications [3].


We’ve discussed Phenibut dosage in-depth in another article, but I’ll provide some brief information here.

First, there have not been any reported deaths from Phenibut [1]. And that is after decades of using it as a medication. So, in that way, it’s safer than alcohol.

Still, you should avoid taking too much of it — like anything. Basically, a normal and safe dose is between 250 mg and 500 mg in one day.

Users start running the risk of negative effects when they start taking more than 1 g in a single dose or more than 2 grams in a single day. So the overdose level is about 8 times a standard 250 mg dose. That means you’re really unlikely to take too much by accident.

If you do take too much, some of the negative effects that you might experience include:

  • Severe drowsiness
  • Nausea
  • Vomiting
  • Lowered blood pressure
  • Impairment of the kidneys
  • Fatty liver degeneration
  • Sometimes even…psychosis [4]

Again, it’s easy to avoid these. Just stick to a normal dose, and stay under 2 grams in one day. Most users take much less than that.

Phenibut Withdrawal | What You MUST Know

Okay, so what about Phenibut Withdrawal effects?

Now we’re getting to the meat and potatoes of this bad boy.

Basically, withdrawal happens like this. When you take Phenibut occasionally, it has a similar effect to the GABA that’s already in your system. That means that both the natural GABA and the Phenibut are in your system, and they work together to create their uplifting effect.

You feel great, your stress goes down, and you sleep better.

Over time, if you continue to use it, your body begins to develop a tolerance for Phenibut [5]. It also starts to slow down the production of your natural GABA. Since your body gets used to getting it from an outside source, it starts to reduce the amount that it produces naturally.

That’s when you start to develop a physical dependence. Your body starts to begin to need Phenibut to work normally [5]. And you may need higher and higher doses to get the same effects as before.

Withdrawal happens when a person develops tolerance and then stops taking Phenibut [6]. Since the body is used to getting the Phenibut and isn’t producing its own GABA, there’s a shock when the Phenibut stops. Since there is neither GABA naturally produced in the body nor the Phenibut that a person is dependent on, there is a lack of this important neurotransmitter [6].


Phenibut Withdrawal Symptoms

Phenibut Withdrawal symptoms can be really uncomfortable [7]. They can include:

  • Rebound anxiety
  • Anger
  • Agitation
  • Irritability
  • Insomnia
  • Auditory and visual hallucinations [8]

Want to avoid Phenibut withdrawal symptoms? Don’t use it too often. Keep your doses under 2 grams in a single day, and use it for a maximum of 2 times a week. Simple.

Or just follow this article about how to take Phenibut properly.

When Does Phenibut Withdrawal Start?

Lots of people are interested in knowing when does Phenibut withdrawal start.

First, a person needs to develop tolerance before they experience withdrawal [8]. As some researchers say, “Tolerance may develop with long-term use” [8]. So physical dependence doesn’t always happen to Phenibut users. If a user does become dependent, it would only be after long term use.

So withdrawal only happens to some long-term users.

Withdrawal usually starts after the last of the Phenibut leaves the system. If your body has become used to getting Phenibut and is no longer making its own GABA, withdrawal effects will start to present after the last Phenibut leaves the system.

They can begin within a few hours of taking Phenibut. However, some users report withdrawal effects beginning several days after they stop taking Phenibut.

Of course, it’s important to note that withdrawal only happens if a person has developed a dependence [8]. That doesn’t just happen from using Phenibut, it happens from using Phenibut regularly over a long period of time [8].

How Long Does Phenibut Withdrawal Last?

How long does Phenibut withdrawal last?

Well, Phenibut withdrawal is different for everyone, so how long it lasts can be different [8].

However, most researchers agree that the acute symptoms can last a couple days [9]. After that, depending on how severe the dependence was, there can be residual effects for a few weeks [8].

How to Treat Your Symptoms

If you think you have a Phenibut dependence, you should get in touch with a physician.

Depending on how much you’re taking and how dependent you are, you may need to create a plan to wean yourself off of it to avoid the worst of the withdrawal effects. Users have said that trying to quit cold turkey can be really unpleasant.
Some medications that have been found to be successful with Phenibut withdrawal include [9]:

  • Phenobarbital
  • Propofol
  • Haloperidol
  • Benzodiazepines
  • Baclofen [8]

However, when dealing with withdrawal effects, it’s probably not a good idea to self-medicate. Instead, bring in a qualified health professional.

In fact…

Do NOT self-medicate when dealing with Phenibut withdrawl. See a professional.

Warnings and Concerns

Anyone taking Phenibut should be careful using it. Like alcohol and other drugs, there is a real risk that people can become dependent on it [8, 9].

You might be at a special risk of developing a dependence on Phenibut if you:

  • have experienced other substance abuse issues
  • have an addictive personality
  • use Phenibut more than three times a week
  • use doses larger than 2 grams a day

Phenibut for Benzo Withdrawal

There are also a bunch of people that use Phenibut for Benzo withdrawal.

Benzodiazepines are a class of drugs used for many psychological conditions, like anxiety, panic disorder, and insomnia. Like Phenibut, it works by mimicking GABA and binding to some GABA receptors [8].

People that use Benzos for a long time can develop dependence issues (in the same way that they can for Phenibut). If a person is dependent on Benzos and stops taking them, they can have withdrawal effects.

Phenibut can help reduce these negative withdrawal effects. They do this because they can sort of make up for the missing effects of GABA. Lots of users have said Phenibut is a bit of a life-saver for taking away awful Benzo withdrawal effects.

However, if you’re trying to get off Benzos, it’s probably best to get in touch with a doctor rather than try to self-medicate your way off them. Sure, Phenibut may be useful, but you want to make sure you’re using them in a safe way.

As I said before, you shouldn’t take Phenibut at the same time as Benzos because you don’t want interaction effects.

Phenibut HCL

Phenibut for Kratom Withdrawal

Kratom is another substance that works through GABA receptors [10].

It’s a plant from the same family as the coffee plant and is native to Southeast Asia. Kratom has opioid properties and is a stimulant. Like other substances, people can become addicted to Kratom and suffer from withdrawal symptoms when they stop taking it [10].

Some users have reported using Phenibut for Kratom withdrawal. We haven’t found any scientific research on this, but it seems reasonable that Phenibut could help reduce the withdrawal effects from Kratom. Kratom works by using a bunch of the same neuron receptors as Phenibut, so it makes sense that Phenibut can help fill in when a person’s body is craving Kratom.

Again, just make sure you’re not hopping from one addiction to the next. If you need help with an addiction, see a professional.

Phenibut for Opiate Withdrawal

Some people use Phenibut for opiate withdrawal.

Opiate withdrawal symptoms can be really intense, and people struggling to get off opioids often talk about how difficult they can be. Again, since opioids work by influencing GABA, and since Phenibut also influences GABA, Phenibut can reduce some of the negative opioid withdrawal effects.

But again, as far as we know, there’s not much good research on the use of Phenibut to treat opioid withdrawal symptoms. And, people that are dependent on opioids may be more likely to have a problem with Phenibut dependence.

In general, talk to a healthcare provider for dealing with withdrawal symptoms.

Phenibut for Alcohol Withdrawal

Finally, research reports that individuals use Phenibut for alcohol withdrawal symptoms and alcohol cravings [11, 12].

Indeed, this is one of its licensed uses in Russia: treatment of alcohol dependence [1].

Because it triggers some of the same receptors as alcohol, some research has found that Phenibut can be an effective way to reduce the discomfort from alcohol withdrawal [13, 14].

Phenibut does seem like a much better alternative to alcohol, but again, just be careful not to go from one addiction to the other.

Buy Phenibut Online | 2020 Guide

Phenibut is legal in almost all countries, and you can buy it easily and safely online. The only thing is to make sure that you find a legitimate supplier.

I’ve been through a few of them myself, and some are much better than others. The trick is to avoid the scammers.

I’ve included a link below which will take you to the site where I recommend people buy Phenibut online. They offer good prices, they ship anywhere, and they won’t scam you.

Phenibut Withdrawal | Verdict

Phenibut offers crazy good benefits, but there is a risk of dependence and withdrawal. Basically, every drug could lead to dependence, and Phenibut isn’t an exception.

How can you avoid Phenibut withdrawal and dependence?

  • Take it a max of two times a week
  • Don’t take more than 2 grams a day
  • Cycle off of it for a month or two every once in a while
  • Don’t use it if you have an addictive personality

If you use it safely, you should be fine. But it’s always good to know about the risks.

Click here to order Phenibut from the best online vendor!


  1. Lapin I. (2001). Phenibut (beta-phenyl-GABA): a tranquilizer and nootropic drug. CNS drug reviews, 7(4), 471–481. doi:10.1111/j.1527-3458.2001.tb00211.x
  2. Cheung, J. & Penn, J. (2018). Weekly dose: Phenibut. The Conversation.
  3. Ozon Pharm (n.d.), Fenibut (PDF). [In Russian].
  4. Högberg, L., Szabó, I., & Ruusa, J. (2013). Psychotic symptoms during phenibut (beta-phenyl-gamma-aminobutyric acid) withdrawal. Journal of Substance Use, 18(4), 335-338.
  5. Koob, G. F. (1996). Drug addiction: the yin and yang of hedonic homeostasis. Neuron, 16(5), 893-896.
  6. Jouney, E. A. (2019). Phenibut (β-Phenyl-γ-Aminobutyric Acid): An easily obtainable “dietary supplement” with propensities for physical dependence and addiction. Current Psychiatry Reports, 21(4), 23.
  7. Joshi, Y. B., Friend, S. F., Jimenez, B., & Steiger, L. R. (2017). Dissociative intoxication and prolonged withdrawal associated with phenibut: a case report. Journal of Clinical Psychopharmacology, 37(4), 478.
  8. Ahuja, T., Mgbako, O., Katzman, C., & Grossman, A. (2018). Phenibut (β-Phenyl-γ-aminobutyric Acid) Dependence and Management of Withdrawal: Emerging Nootropics of Abuse. Case reports in psychiatry, 2018. doi:10.1155/2018/9864285
  9. Hardman, M. I., Sprung, J., & Weingarten, T. N. (2019). Acute phenibut withdrawal: A comprehensive literature review and illustrative case report. Bosnian Journal of Basic Medical Sciences, 19(2), 125.
  10. Singh, D., Müller, C. P., & Vicknasingam, B. K. (2014). Kratom (Mitragyna speciosa) dependence, withdrawal symptoms and craving in regular users. Drug and alcohol dependence, 139, 132-137.
  11. Samokhvalov, A. V., Paton-Gay, C. L., Balchand, K., & Rehm, J. (2013). Phenibut dependence. Case Reports, 2013, bcr2012008381.
  12. Zheng, K. H., Khan, A., & Espiridion, E. D. (2019). Phenibut Addiction in a Patient with Substance Use Disorder. Cureus, 11(7).
  13. Tiurenkov, I. N., Voronkov, A. V., & Borodkina, L. E. (2005). Effect of phenibut on the behavior of experimental animals under conditions of voluntary chronic alcoholism. Eksperimental’naia i Klinicheskaia Farmakologiia, 68(3), 42-45.
  14. Danilin, V. P., Krylov, E. N., AIu, M., & Rait, M. L. (1986). Effect of fenibut on the nocturnal sleep of patients with the alcoholic abstinence syndrome. Zhurnal nevropatologii i psikhiatrii imeni SS Korsakova (Moscow, Russia: 1952), 86(2), 251-254.


After utilizing nootropics for the better part of a decade, I realized the potent results these products produce -- with regards to productivity and cognitive enhancement. Soon thereafter, I became obsessed with finding the premier smart drugs on the market. Then using them to improve my life. When I'm not devouring everything I can about nootropics and the science behind why they work, you'll find me traveling around the world or in the gym.

Click Here to Leave a Comment Below

Leave a Reply: