Phenibut Dosage Guide | Uses, Indications, and Microdosing

Looking for information on the perfect, safe Phenibut dosage? Then you’re in the perfect place.

Phenibut is increasingly being hailed as a wonder drug in “social” situations, with users reporting boosts in mood, feelings of euphoria, reduced anxiety in social situations, and a clearer mind.

It’s improving people’s social life and making them feel better.


Because Phenibut is a substance that depresses the central nervous system, causing a reduction in feelings of anxiety and improving sleep quality. It’s been around since the 1960s when it was discovered by Russian scientists. Since then, it’s been used regularly in several countries, including, Russia, the Ukraine, Belarus, and Latvia, as an anxiety and sleep medication.

While it hasn’t been approved in the United States as a prescription medication, lots of regular people are ordering it as a nutritional supplement and using it for recreational purposes. Since it’s not a controlled substance, it is easy and perfectly legal to get your hands on it over the internet.

P.S: Click here to order Phenibut from the top vendor online!

But while lots of users have reported great results, it’s important to make sure that the right Phenibut dosage is used. This is especially important since, without careful use, people can find that they develop tolerance to it — and even dependence.

This article will give you a complete breakdown of Phenibut dosing guidelines, including Phenibut dosage for sleep, for anxiety, and microdosing.

P.S: It should come as no surprise that I’m not a doctor or a lawyer. This is not legal or medical advice. The information presented on this site is purely entertainment. Always consult a medical professional before consuming any nootropics. Full disclaimer.

What is Phenibut?

Let’s start with the basics. What actually is Phenibut?

Phenibut (β‐phenyl‐γ‐aminobutyric acid HCl) is a neuropsychotropic drug, which means it’s a drug that has an effect on the nervous system [1].

It is usually taken orally in a tablet or as a salt or powder dissolved in water, but it can also be applied intravenously. It is sold under several trade names including Anvifen, Fenibut, Noofen, and others.

It’s sometimes called a “tranquilizer” drug, but not because it’s actually used as a tranquilizer. The name refers to the fact that it has a depressant effect on the central nervous system.

When used in appropriately small doses, this has the effect of depressing some parts of the brain that are responsible for higher-order thinking, similar to alcohol. These are the parts of your brain that, when they’re overly excited, make you feel stressed and worried. By calming down these parts of the brain, Phenibut can help reduce worry and anxiety. It also helps the user get better, more restful sleep [1].

While it has some similar effects to alcohol, there are some important differences: Phenibut does not come with uncomfortable, “drunk”-like symptoms or foggy thinking. Indeed, it is considered a nootropic, which means it has some cognitive-enhancing effects. It actually helps combat the “foggy brain” in many ways.

How Does It Work?

Well, Phenibut is chemically similar to γ-aminobutyric acid, also called GABA, which is a neurotransmitter that is found in your brain and nervous system. Because it is similar to GABA, it can bind to the same receptors that GABA can and can therefore have some of the same effects.

GABA is a neurotransmitter that inhibits activity. If you think of your neurons like light switches, GABA is responsible for turning off the lights after other neurotransmitters turn them on. It plays an important role in reducing neuronal excitability in the nervous system.

Like GABA, Phenibut is an agonist of the GABAb receptor, which means that it also has a role in inhibiting neural functions and reducing excitability. That is why it is commonly used to help people relax, control anxiety, and to aid in sleep [1]. It basically helps calm the brain down.

Also, at low levels, it’s been found to increase dopamine levels slightly, which results in a pleasurable, euphoric feeling.
Phenibut dosing is widely used throughout the countries of the former USSR, like Russia, Belarus, and Latvia for relieving tension, anxiety, and fear.

It’s also used to improve sleep in a number of different kinds of patients. Sometimes it’s also used in the therapy of asthenia and depression, and in other anxiety disorders like post-traumatic stress syndrome. It’s also been known to be used as a treatment for stuttering and other vestibular disorders [1].

In countries where it is not an approved medical treatment, lots of users use Phenibut recreational dosage as a recreational drug because it can result in feelings of euphoria and increases sociability. Some people also use it to self-medicate and reduce feelings of social anxiety.

Phenibut HCL

Phenibut Side Effects and Safety

In general, Phenibut dosing is considered quite safe. It’s well tolerated by the majority of research subjects and users. However, there are some side effects that users should be aware of, as well as the effects of withdrawal and of overdose.

Here we’ll give you the rundown about what can happen, but keep in mind these effects are rare. And, in the case of overdosing and Phenibut withdrawal effects, you’re only going to see these if you’re using it badly.

If you follow our Phenibut dosage guidelines, you’ll avoid these adverse effects.

Side Effects

Some Phenibut side effects that have been reported. Here is a shortlist of the more common and less severe side effects of Phenibut [2]:

  • Drowsiness
  • Nausea
  • Irritability
  • Headache
  • Sedation

In addition to these, some more severe side effects can occur in individuals that take Phenibut at very high doses. This can include:

  • Motor incoordination
  • Hangover-like symptoms
  • Loss of balance

Like many substances, some people may experience allergic reactions to Phenibut. These can include skin rash and itching. If you experience allergic reactions or side effects, stop taking it, and get advice from your doctor.

Again, it’s important to stress that the vast majority of people will not experience any side effects.

Interaction Effects

Another thing to note is that Phenibut can interact with other, similar, substances.

Since it works by depressing the central nervous system, Phenibut dosing can interact with other substances that influence the central nervous system, including alcohol, anxiolytics (medication for anxiety), antipsychotic medications, sedatives, opioids, and anticonvulsants.

It can make any of these medications stronger or last longer than normal.

Basically, you shouldn’t use Phenibut with these other types of medication. Of course, anyone considering Phenibut should seek advice from a doctor.

Phenibut Withdrawal Effects

It is important to note that some people who use Phenibut can develop tolerance and a dependence on it [3]. This can, in some cases, look like addiction. This is especially the case for those people who use it regularly for a long time.

Tolerance and dependence do not occur in people who use Phenibut only occasionally.

Tolerance means that with repeated use, the “test subject’s” body gets accustomed to the chemical and stops producing its own GABA. It does this to kind of balance out the GABA levels… since there is already so much Phenibut in the system, the body produces less GABA. Then, when the subject stops taking the Phenibut, the body takes a while to restart its GABA production, so there is some time when there are just low levels of the neurotransmitter.

When the user stops taking the Phenibut, the body is not making its own GABA, and there can be some withdrawal symptoms. Withdrawal symptoms can include [3]:

  • Rebound anxiety
  • Anger
  • Agitation
  • Irritability
  • Insomnia
  • Auditory and visual hallucinations
  • And even psychosis [4]

It’s really easy to avoid these withdrawal effects.

To avoid withdrawal effects, Phenibut should not be taken over a long period of time or regularly [5, 6], except on the instructions of a doctor in those jurisdictions where it is a recognized medication [7, 8].

Generally, anyone considering using Phenibut should:

  • Not take it more than twice a week.
  • Cycle off occasionally for a month or two.

In doing so, side effects should be quite minimal — or even non-existent. Phenibut is a safe smart drug, as long as it’s used in small dosages.

Phenibut Dosage Guide | The Basics

Here’s what users need to know before deciding on what Phenibut dosage to start with…

First, there are two main types of the nootropic:

Phenibut HCL and Phenibut FAA

These products vary slightly:

  • Phenibut HCL is a salt. This is how Phenibut most commonly comes. It’s made from taking the Phenibut free amino acid and getting it to react with hydrochloric acid. This means it’s an ionic salt. You can ingest it in this form by dissolving it in warm water and then drinking it. Sometimes it comes in a capsule form. Take with citrus juice to clear away the bitter taste.
  • Phenibut FAA is the free-form amino acid. It is a newer version of Phenibut and is not as dissolvable. Instead of putting it in water, it can be taken by putting it under the tongue where it takes several minutes to be absorbed. It is usually a bit more expensive.

Both Phenibut HCL and Phenibut FAA are the same chemical substance. Phenibut FAA typically has a bit more of the chemical by weight just because of how it’s produced. That means you should take a bit less of it. It’s also a bit more expensive.

See below for more detailed guidance on how to take Phenibut in each of these two forms.

Great, so how much Phenibut should I take?

How much Phenibut a “test subject” should take in a dose depends on a few factors:

  • The “test subject’s” body size. All other things being equal, larger people need more Phenibut to feel the same effects.
  • The “test subject’s” age. Older people should generally take less than younger people.
  • The “test subject’s” health. People with health issues should take less than those who are totally healthy. People with chronic conditions, liver issues, or kidney issues should probably not take it.
  • The effect you want. See below for more guidance on this.

That makes it difficult to provide suggestions since everyone’s bodies are different. There are some guidelines below. But generally, the best advice for anyone is to start low and then increase gradually.

Usually, individuals could start with a small dose of even just 50mg and see how it feels. Then they can go up slowly, in 50mg increments, to find their ideal dose.

One thing that people who are new to Phenibut should remember is that there is a bit of a lag between when you take it and when you feel its effect. Some people accidentally take an additional dose because they don’t feel it working [1].

Also, take it at least an hour before eating. You want to have an empty stomach.

How long will it last?

The half-life for Phenibut is about 5 to 6 hours. That means that after 5 hours, your body will have metabolized half of it. But that time, you will stop feeling its effects. Of course, the length of time you’ll feel the effects depends a bit on your own body and how much you take.

As a rough guideline, if you take 250mg, you can expect that it will last about 5 hours. But some people report feeling its effects for up to 24 hours [5].

Phenibut HCL powder

Phenibut FAA Dosing Guidelines

Phenibut FAA dosage doesn’t mix well with liquids, so you generally don’t want to try to dissolve in a drink. Instead, you can put it under your tongue and wait for it to absorb. This usually tastes bad.

Other users fold it up in dissolvable paper and swallow it. Putting it in capsules is another popular method.

Because the Phenibut FAA dosage has more Phenibut in it than it does in the HCL form, one needs slightly less of it. 250mg of Phenibut FAA is about the same as 400mg of Phenibut HCL. So just keep that in mind when you’re choosing your dose: make it a bit smaller for FAA.

For beginners, try the following Phenibut FAA dosage:

  • 250mg to 350mg
  • split into 1 to 3 doses per day
  • Take it at least an hour before food, aka on an empty stomach

This should ensure the Phenibut “hits” just right and you enter a positive, social state of mind within 60-120 minutes. Phenibut does take up to two hours to kick in.

Phenibut HCL Dosing Guidelines

Phenibut HCL dosage is an ionic salt which means that it dissolves easily in water or other beverages. This is a common way that users take it. The most common other way is simply by taking it as a capsule.

Phenibut HCL typically has less Phenibut by mass than the FAA type, which means your doses might be slightly higher than for FAA.

For beginners, try the following Phenibut HCL dosage:

  • 350mg to 500mg
  • split into 1 to 3 doses per day
  • Take it at least an hour before food, aka on an empty stomach

By following this dosing plan, you’ll enjoy the benefits of Phenibut without much, or any, side effects. Exactly what we’re looking for when taking smart drugs for social purposes.

Phenibut Dosage For Anxiety

To feel calmer, individuals usually start with a relatively low dose of:

  • 250mg to 350mg
  • split into 1 to 3 doses per day
  • Take it at least an hour before food as food interrupts how it is absorbed

This Phenibut dosage for anxiety will generally help one improve their mood and have a general sense of calmness. They may feel more sociable at this lower dose.

Phenibut Dosage For Sleep

Individuals can increase the dose somewhat to get benefits for sleep. An appropriate Phenibut dosage for sleep would be between

  • 500mg to 750mg
  • split into 1 to 3 doses per day
  • Take it at least an hour before food

This higher dose will give the same boost to mood and anti-anxiety effects as the lower dose, but it will also help you get better sleep.

Microdosing Phenibut?

Some users have reported that Phenibut can have a good effect in even very small doses. It looks like Phenibut recreational dosage may even provide a protective effect on the cardiovascular system by reducing the negative effects of stress.

In addition, the nootropic effects of Phenibut typically happen at small doses, less than 20mg per kilogram of body weight [6].

Others have reported that it’s great for just getting that extra bit of restful sleep.

If you’re interested in a microdose, try this:

  • 50mg to 100mg
  • 1 time per day
  • Take it at least an hour before food

It might also be a good idea for individuals to start with a microdose to see how their body reacts to it. Then they can increase the dose by about 50mg to get to a point where they are enjoying the resulting effects.

Phenibut dosage

Lethal Dosage?

Phenibut is generally considered safe. And, what’s more, there have been no reported deaths associated with Phenibut [4]. While there could be a dose that is lethal, it is sufficiently high that virtually everyone using the drug would not take such a dose by accident.

However, there are several uncomfortable effects associated with overdosing or taking a dose that is significantly more than what is recommended in the Phenibut dosing guidelines listed above.

Overdosing on Phenibut can cause:

  • Severe drowsiness
  • Nausea
  • Vomiting
  • Lowered blood pressure
  • Impairment of the kidneys
  • And fatty liver degeneration

Individuals that have overdosed also may experience short term changes in consciousness or state, including lethargy, agitation, delirium, reduced consciousness, or even unconsciousness.

It’s generally not recommended to take over 1 gram per dose or 2mg per day. It’s also not recommended to use it more than 2 times per week [4].

Also, just to reiterate:

Do NOT mix with alcohol or benzodiazepines since these have the same effect that Phenibut does, and can increase the actions of the other, leading to bad effects.

Using them together makes a person more likely to overdose.

Phenibut Dosing | The Verdict

Phenibut is a great nootropic and perfectly legal. Users report that it can help them feel relaxed, less stressed, more sociable, and just generally improve their mood. It’s also great for insomnia.

I’ve given detailed Phenibut dosing information above based on what users and “test subjects” have found effective. Of course, starting with a low dose and gradually increasing is always the best practice.

While there are some side effects, users say that following these guidelines help them avoid any negative experiences:

  • Don’t use with other depressants like alcohol
  • Don’t use more than 1g in a dose
  • Don’t use more than 2g a day
  • Don’t use more than 2 times a week
  • Cycle off every once in a while to avoid dependence

Follow those dosage guidelines and this “Russian wonder drug” could be the key to a whole new outlook. You’ll feel social without needing to drink or suffering horrific hangovers!

 To get started using Phenibut, click here to buy the smart drug from our #1 recommended online vendor.


  1. Lapin I. (2001). Phenibut (beta-phenyl-GABA): a tranquilizer and nootropic drug. CNS drug reviews, 7(4), 471–481. doi:10.1111/j.1527-3458.2001.tb00211.x
  2. Cheung, J. & Penn, J. (2018). Weekly dose: Phenibut. The Conversation.
  3. Ahuja, T., Mgbako, O., Katzman, C., & Grossman, A. (2018). Phenibut (β-Phenyl-γ-aminobutyric Acid) Dependence and Management of Withdrawal: Emerging Nootropics of Abuse. Case reports in psychiatry, 2018. doi:10.1155/2018/9864285
  4. Högberg, L., Szabó, I., & Ruusa, J. (2013). Psychotic symptoms during Phenibut (beta-phenyl-gamma-aminobutyric acid) withdrawal. Journal of Substance Use, 18(4), 335-338.
  5. Owen, D. R., Wood, D. M., Archer, J. R., & Dargan, P. I. (2016). Phenibut (4‐amino‐3‐phenyl‐butyric acid): Availability, prevalence of use, desired effects and acute toxicity. Drug and alcohol review, 35(5), 591-596.
  6. Zheng, K. H., Khan, A., & Espiridion, E. D. (2019). Phenibut Addiction in a Patient with Substance Use Disorder. Cureus, 11(7).
  7. Samokhvalov, A. V., Paton-Gay, C. L., Balchand, K., & Rehm, J. (2013). Phenibut dependence. Case Reports, 2013, bcr2012008381.
  8. Jouney, E. A. (2019). Phenibut (β-Phenyl-γ-Aminobutyric Acid): An easily obtainable “dietary supplement” with propensities for physical dependence and addiction. Current Psychiatry Reports, 21(4), 23.


After utilizing nootropics for the better part of a decade, I realized the potent results these products produce -- with regards to productivity and cognitive enhancement. Soon thereafter, I became obsessed with finding the premier smart drugs on the market. Then using them to improve my life. When I'm not devouring everything I can about nootropics and the science behind why they work, you'll find me traveling around the world or in the gym.

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